Police said the cyclist, Barron Sanders, was found lying on the ground at the intersection of Marcus Garvey Boulevard and Park Avenue in Bushwick with severe head trauma at 7:49 p.m.
Friends and neighbors outside of Sanders's home on Marcy Avenue said the place where the accident occurred is not known as a dangerous intersection.
A woman who identified herself as family friend, Debra Clinton, said Sanders was just about to enter fatherhood.
"He and his wife were expecting their first child. They just had a baby shower. He's never gonna see his little girl. And on top of this, it's Mother's Day tomorrow," she said. She described him as "a lovable, friendly guy."
"He was a very special man and everyone will miss him badly," she added.
According to police, Sanders was driving his 2008 Kawasaki motorcycle eastbound on Park Avenue when a man, 68, driving a black 2007 Chevy Impala sedan, traveling westbound on Park Avenue at the intersection of Marcus Garvey Boulevard (which is also called Sumner Avenue).
Police said the driver of the black sedan remained at the scene, and that there is no criminality suspected at this time. Police say the investigation is ongoing.
Sanders was transported to Kings County Hospital, and pronounced dead on arrival.